Before opening sachet, use fingertips to gently distribute serum evenly. Open the sachet, take out mask and carefully unfold. Remove and discard the protective outer layers. Place the Bio-Cellulose sheet onto the face, adjusting the eye, nose and mouth openings. Gently smooth mask over entire face, eliminating any folds or air pockets. Leave on for 15-20 minutes before removing the mask. Gently pat any remaining serum into the skin – no rinsing necessary.